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Other Issues:
 May 2005, Volume 25, Issue 9   [Index by Author] 
       Instructions to Authors (none in this issue)
       Guest Commentaries (none in this issue)
       Minireviews (none in this issue)
       Gene Expression
       Chromosome Structure and Dynamics
       Signal Transduction
       Intracellular Trafficking
       Mammalian Genetic Models with Minimal or Complex Phenotypes
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Gene Expression:
Whole-Genome Analysis Reveals a Strong Positional Bias of Conserved dMyc-Dependent E-Boxes
   Toby Hulf, Paola Bellosta, Michael Furrer, Dominik Steiger, David Svensson, Andrew Barbour, and Peter Gallant
Mol. Cell. Biol. 2005. 25: 3401-3410. [Abstract] [HTML] [PDF] [Supplemental material]  
 
cis-Regulatory Logic of Short-Range Transcriptional Repression in Drosophila melanogaster
   Meghana M. Kulkarni and David N. Arnosti
Mol. Cell. Biol. 2005. 25: 3411-3420. [Abstract] [HTML] [PDF]  
 
SPBP Is a Phosphoserine-Specific Repressor of Estrogen Receptor {alpha}
   Valentina Gburcik, Nathalie Bot, Marcello Maggiolini, and Didier Picard
Mol. Cell. Biol. 2005. 25: 3421-3430. [Abstract] [HTML] [PDF]  
 
Adult Stage {gamma}-Globin Silencing Is Mediated by a Promoter Direct Repeat Element
   Akane Omori, Osamu Tanabe, James Douglas Engel, Akiyoshi Fukamizu, and Keiji Tanimoto
Mol. Cell. Biol. 2005. 25: 3443-3451. [Abstract] [HTML] [PDF]  
 
Sequence-Specific DNA Binding by the {alpha}NAC Coactivator Is Required for Potentiation of c-Jun-Dependent Transcription of the Osteocalcin Gene
   Omar Akhouayri, Isabelle Quélo, and René St-Arnaud
Mol. Cell. Biol. 2005. 25: 3452-3460. [Abstract] [HTML] [PDF]  
 
Interdependent Recruitment of SAGA and Srb Mediator by Transcriptional Activator Gcn4p
   Hongfang Qiu, Cuihua Hu, Fan Zhang, Gwo Jiunn Hwang, Mark J. Swanson, Cheunchit Boonchird, and Alan G. Hinnebusch
Mol. Cell. Biol. 2005. 25: 3461-3474. [Abstract] [HTML] [PDF]  
 
Orphan Nuclear Receptor LRH-1 Is Required To Maintain Oct4 Expression at the Epiblast Stage of Embryonic Development
   Peili Gu, Bryan Goodwin, Arthur C.-K. Chung, Xueping Xu, David A. Wheeler, Roger R. Price, Cristin Galardi, Li Peng, Anne M. Latour, Beverly H. Koller, Jan Gossen, Steven A. Kliewer, and Austin J. Cooney
Mol. Cell. Biol. 2005. 25: 3492-3505. [Abstract] [HTML] [PDF]  
 
Identification In Vivo of Different Rate-Limiting Steps Associated with Transcriptional Activators in the Presence and Absence of a GAGA Element
   Yunyuan Vivian Wang, Hongbing Tang, and David S. Gilmour
Mol. Cell. Biol. 2005. 25: 3543-3552. [Abstract] [HTML] [PDF]  
 
Inhibition of Human Chk1 Causes Increased Initiation of DNA Replication, Phosphorylation of ATR Targets, and DNA Breakage
   Randi G. Syljuåsen, Claus Storgaard Sørensen, Lasse Tengbjerg Hansen, Kasper Fugger, Cecilia Lundin, Fredrik Johansson, Thomas Helleday, Maxwell Sehested, Jiri Lukas, and Jiri Bartek
Mol. Cell. Biol. 2005. 25: 3553-3562. [Abstract] [HTML] [PDF]  
 
Id2 Mediates Tumor Initiation, Proliferation, and Angiogenesis in Rb Mutant Mice
   Anna Lasorella, Gerson Rothschild, Yoshifumi Yokota, Robert G. Russell, and Antonio Iavarone
Mol. Cell. Biol. 2005. 25: 3563-3574. [Abstract] [HTML] [PDF]  
 
Myocyte Enhancer Factor 2 Acetylation by p300 Enhances Its DNA Binding Activity, Transcriptional Activity, and Myogenic Differentiation
   Kewei Ma, Jonathan K. L. Chan, Guang Zhu, and Zhenguo Wu
Mol. Cell. Biol. 2005. 25: 3575-3582. [Abstract] [HTML] [PDF]  
 
Human RNA Polymerase II Elongation in Slow Motion: Role of the TFIIF RAP74 {alpha}1 Helix in Nucleoside Triphosphate-Driven Translocation
   Chunfen Zhang, Katie L. Zobeck, and Zachary F. Burton
Mol. Cell. Biol. 2005. 25: 3583-3595. [Abstract] [HTML] [PDF]  
 
The Mcp Element from the bithorax Complex Contains an Insulator That Is Capable of Pairwise Interactions and Can Facilitate Enhancer-Promoter Communication
   Natalia Gruzdeva, Olga Kyrchanova, Alexander Parshikov, Andrey Kullyev, and Pavel Georgiev
Mol. Cell. Biol. 2005. 25: 3682-3689. [Abstract] [HTML] [PDF]  
 
Direct p53 Transcriptional Repression: In Vivo Analysis of CCAAT-Containing G2/M Promoters
   Carol Imbriano, Aymone Gurtner, Fabienne Cocchiarella, Silvia Di Agostino, Valentina Basile, Monica Gostissa, Matthias Dobbelstein, Giannino Del Sal, Giulia Piaggio, and Roberto Mantovani
Mol. Cell. Biol. 2005. 25: 3737-3751. [Abstract] [HTML] [PDF]  
 
Small Interfering RNAs That Trigger Posttranscriptional Gene Silencing Are Not Required for the Histone H3 Lys9 Methylation Necessary for Transgenic Tandem Repeat Stabilization in Neurospora crassa
   Agustin Chicas, Emma C. Forrest, Silvia Sepich, Carlo Cogoni, and Giuseppe Macino
Mol. Cell. Biol. 2005. 25: 3793-3801. [Abstract] [HTML] [PDF] [Supplemental material]  
 
Defining the Order in Which Nmd3p and Rpl10p Load onto Nascent 60S Ribosomal Subunits
   Matthew West, John B. Hedges, Anthony Chen, and Arlen W. Johnson
Mol. Cell. Biol. 2005. 25: 3802-3813. [Abstract] [HTML] [PDF]  
 

Chromosome Structure and Dynamics:
Recql5 and Blm RecQ DNA Helicases Have Nonredundant Roles in Suppressing Crossovers
   Yiduo Hu, Xincheng Lu, Ellen Barnes, Min Yan, Hua Lou, and Guangbin Luo
Mol. Cell. Biol. 2005. 25: 3431-3442. [Abstract] [HTML] [PDF]  
 
Mismatch Repair Proteins Are Activators of Toxic Responses to Chromium-DNA Damage
   Elizabeth Peterson-Roth, Mindy Reynolds, George Quievryn, and Anatoly Zhitkovich
Mol. Cell. Biol. 2005. 25: 3596-3607. [Abstract] [HTML] [PDF]  
 
The Human Stress-Activated Protein kin17 Belongs to the Multiprotein DNA Replication Complex and Associates In Vivo with Mammalian Replication Origins
   Laurent Miccoli, Isabelle Frouin, Olivia Novac, Domenic Di Paola, Francis Harper, Maria Zannis-Hadjopoulos, Giovanni Maga, Denis S. F. Biard, and Jaime F. Angulo
Mol. Cell. Biol. 2005. 25: 3814-3830. [Abstract] [HTML] [PDF]  
 

Signal Transduction:
The Mechanism of Endogenous Receptor Activation Functionally Distinguishes Prototype Canonical and Noncanonical Wnts
   Guizhong Liu, Anna Bafico, and Stuart A. Aaronson
Mol. Cell. Biol. 2005. 25: 3475-3482. [Abstract] [HTML] [PDF]  
 
FAT10, a Ubiquitin-Independent Signal for Proteasomal Degradation
   Mark Steffen Hipp, Birte Kalveram, Shahri Raasi, Marcus Groettrup, and Gunter Schmidtke
Mol. Cell. Biol. 2005. 25: 3483-3491. [Abstract] [HTML] [PDF]  
 
SUMO-1 Modification of PIASy, an E3 Ligase, Is Necessary for PIASy-Dependent Activation of Tcf-4
   Motomasa Ihara, Hideki Yamamoto, and Akira Kikuchi
Mol. Cell. Biol. 2005. 25: 3506-3518. [Abstract] [HTML] [PDF]  
 
The Pleckstrin Homology Domain-Containing Protein CKIP-1 Is Involved in Regulation of Cell Morphology and the Actin Cytoskeleton and Interaction with Actin Capping Protein
   David A. Canton, Mary Ellen K. Olsten, Kyoungtae Kim, Amanda Doherty-Kirby, Gilles Lajoie, John A. Cooper, and David W. Litchfield
Mol. Cell. Biol. 2005. 25: 3519-3534. [Abstract] [HTML] [PDF]  
 
Induction of Ectopic Olfactory Structures and Bone Morphogenetic Protein Inhibition by Rossy, a Group XII Secreted Phospholipase A2
   Ignacio Muñoz-Sanjuán and Ali H. Brivanlou
Mol. Cell. Biol. 2005. 25: 3608-3619. [Abstract] [HTML] [PDF]  
 
Caspase-3-Dependent ß-Cell Apoptosis in the Initiation of Autoimmune Diabetes Mellitus
   Nicole Liadis, Kiichi Murakami, Mohamed Eweida, Alisha R. Elford, Laura Sheu, Herbert Y. Gaisano, Razqallah Hakem, Pamela S. Ohashi, and Minna Woo
Mol. Cell. Biol. 2005. 25: 3620-3629. [Abstract] [HTML] [PDF]  
 
The Phosphatidylinositol 3-Phosphate Phosphatase Myotubularin- Related Protein 6 (MTMR6) Is a Negative Regulator of the Ca2+-Activated K+ Channel KCa3.1
   Shekhar Srivastava, Zhai Li, Lin Lin, GongXin Liu, Kyung Ko, William A. Coetzee, and Edward Y. Skolnik
Mol. Cell. Biol. 2005. 25: 3630-3638. [Abstract] [HTML] [PDF]  
 
Integrin-Linked Kinase Mediates Bone Morphogenetic Protein 7-Dependent Renal Epithelial Cell Morphogenesis
   Chungyee Leung-Hagesteijn, Ming Chang Hu, Ahalya S. Mahendra, Sunny Hartwig, Henry J. Klamut, Norman D. Rosenblum, and Gregory E. Hannigan
Mol. Cell. Biol. 2005. 25: 3648-3657. [Abstract] [HTML] [PDF]  
 
Tyrosine Phosphorylation Regulates Maturation of Receptor Tyrosine Kinases
   Dirk-E. Schmidt-Arras, Annette Böhmer, Boyka Markova, Chunaram Choudhary, Hubert Serve, and Frank-D. Böhmer
Mol. Cell. Biol. 2005. 25: 3690-3703. [Abstract] [HTML] [PDF]  
 
Caspase-Dependent Regulation and Subcellular Redistribution of the Transcriptional Modulator YY1 during Apoptosis
   Anja Krippner-Heidenreich, Gesa Walsemann, Maroun J. Beyrouthy, Stefanie Speckgens, Regine Kraft, Hubert Thole, Robert V. Talanian, Myra M. Hurt, and Bernhard Lüscher
Mol. Cell. Biol. 2005. 25: 3704-3714. [Abstract] [HTML] [PDF]  
 
Interaction of BAG1 and Hsp70 Mediates Neuroprotectivity and Increases Chaperone Activity
   Jan Liman, Sundar Ganesan, Christoph P. Dohm, Stan Krajewski, John C. Reed, Mathias Bähr, Fred S. Wouters, and Pawel Kermer
Mol. Cell. Biol. 2005. 25: 3715-3725. [Abstract] [HTML] [PDF] [Supplemental material]  
 
p21-Activated Kinase 1 Regulates Microtubule Dynamics by Phosphorylating Tubulin Cofactor B
   Ratna K. Vadlamudi, Christopher J. Barnes, Suresh Rayala, Feng Li, Seetharaman Balasenthil, Stevan Marcus, Holly V. Goodson, Aysegul A. Sahin, and Rakesh Kumar
Mol. Cell. Biol. 2005. 25: 3726-3736. [Abstract] [HTML] [PDF]  
 
Cyclins D2 and D1 Are Essential for Postnatal Pancreatic ß-Cell Growth
   Jake A. Kushner, Maria A. Ciemerych, Ewa Sicinska, Lynn M. Wartschow, Monica Teta, Simon Y. Long, Piotr Sicinski, and Morris F. White
Mol. Cell. Biol. 2005. 25: 3752-3762. [Abstract] [HTML] [PDF]  
 
Interaction of Paxillin with Poly(A)-Binding Protein 1 and Its Role in Focal Adhesion Turnover and Cell Migration
   Alison J. Woods, Theodoros Kantidakis, Hisataka Sabe, David R. Critchley, and Jim C. Norman
Mol. Cell. Biol. 2005. 25: 3763-3773. [Abstract] [HTML] [PDF]  
 
Selective Regulation of c-jun Gene Expression by Mitogen-Activated Protein Kinases via the 12-O-Tetradecanoylphorbol-13-Acetate- Responsive Element and Myocyte Enhancer Factor 2 Binding Sites
   Midori Kayahara, Xin Wang, and Cathy Tournier
Mol. Cell. Biol. 2005. 25: 3784-3792. [Abstract] [HTML] [PDF]  
 
Dok-R Mediates Attenuation of Epidermal Growth Factor-Dependent Mitogen-Activated Protein Kinase and Akt Activation through Processive Recruitment of c-Src and Csk
   Paul Van Slyke, Mariano Loza Coll, Zubin Master, Harold Kim, Jorge Filmus, and Daniel J. Dumont
Mol. Cell. Biol. 2005. 25: 3831-3841. [Abstract] [HTML] [PDF]  
 
Proteasomal ATPase-Associated Factor 1 Negatively Regulates Proteasome Activity by Interacting with Proteasomal ATPases
   Yoon Park, Yong-Pil Hwang, Jong-Sik Lee, Sang-Hyun Seo, Sungjoo Kim Yoon, and Jong-Bok Yoon
Mol. Cell. Biol. 2005. 25: 3842-3853. [Abstract] [HTML] [PDF]  
 

Intracellular Trafficking:
An Evolutionarily Conserved Coiled-Coil Protein Implicated in Polycystic Kidney Disease Is Involved in Basal Body Duplication and Flagellar Biogenesis in Trypanosoma brucei
   Gareth W. Morgan, Paul W. Denny, Sue Vaughan, David Goulding, Tim R. Jeffries, Deborah F. Smith, Keith Gull, and Mark C. Field
Mol. Cell. Biol. 2005. 25: 3774-3783. [Abstract] [HTML] [PDF] [Supplemental material]  
 

Mammalian Genetic Models with Minimal or Complex Phenotypes:
Inactivation of CtIP Leads to Early Embryonic Lethality Mediated by G1 Restraint and to Tumorigenesis by Haploid Insufficiency
   Phang-Lang Chen, Feng Liu, Suna Cai, Xiaoqin Lin, Aihua Li, Yumay Chen, Bingnan Gu, Eva Y.-H. P. Lee, and Wen-Hwa Lee
Mol. Cell. Biol. 2005. 25: 3535-3542. [Abstract] [HTML] [PDF]  
 
Targeted Disruption of Tgif, the Mouse Ortholog of a Human Holoprosencephaly Gene, Does Not Result in Holoprosencephaly in Mice
   Jun Shen and Christopher A. Walsh
Mol. Cell. Biol. 2005. 25: 3639-3647. [Abstract] [HTML] [PDF] [Supplemental material]  
 
The Distal Sequence Element of the Selenocysteine tRNA Gene Is a Tissue-Dependent Enhancer Essential for Mouse Embryogenesis
   Vincent P. Kelly, Takafumi Suzuki, Osamu Nakajima, Tsuyoshi Arai, Yoshitaka Tamai, Satoru Takahashi, Susumu Nishimura, and Masayuki Yamamoto
Mol. Cell. Biol. 2005. 25: 3658-3669. [Abstract] [HTML] [PDF]  
 
Role of MLK3 in the Regulation of Mitogen-Activated Protein Kinase Signaling Cascades
   Deborah Brancho, Juan-Jose Ventura, Anja Jaeschke, Beth Doran, Richard A. Flavell, and Roger J. Davis
Mol. Cell. Biol. 2005. 25: 3670-3681. [Abstract] [HTML] [PDF]  
 

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